MMI Director presented invited lecture at the Karolinska Institute, Stockholm, Sweden, Sept. 9, 2022

The lecture entitled “Porosome-mediated cell secretion” expanded on the porosome discovery and its impact on intercellular communication to maintain homeostasis in an organism. Secretion is a fundamental process through which cells communicate with their environment and exchange information in a multicellular context to reach homeostasis and sustain life. The nanoscale transmembrane cup-shaped lipoprotein structure discovered by Prof. Jena and named the ‘porosome’ has since the original discovery in 1996, been implicated in a wide range of secretory events such as neurotransmission, hormone and digestive enzyme release, and the release of exosome-like vesicular bodies from cells.